| 存储条件 |
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| Product Name | CD62P [JM10-95] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB,IHC |
| WB:1:1,000-1:2,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Antigen CD62 antibody CD62 antibody CD62 antigen-like family member P antibody CD62P antibody GMP 140 antibody GMP-140 antibody GMP140 antibody GMRP antibody Granule membrane protein 140 antibody Granulocyte membrane protein antibody GRMP antibody LECAM 3 antibody LECAM3 antibody Leukocyte endothelial cell adhesion molecule 3 antibody Leukocyte-endothelial cell adhesion molecule 3 antibody LYAM3_HUMAN antibody P Selectin antibody P-selectin antibody PADGEM antibody Platelet activation dependent granule-external membrane protein antibody Platelet alpha granule membrane protein antibody PSEL antibody Selectin P (granule membrane protein 140kDa antigen CD62) antibody SELP antibody |
|---|---|
| Molecular Weight(MW) | 100 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | P16109 |
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Application
Fig1: Western blot analysis of CD62P on different cells lysates using anti-CD62P antibody at 1/500 dilution. Positive control: Line1: HUVEC Line2: Human placenta
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD62P antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD62P antibody. Counter stained with hematoxylin.| Positive Control | HUVEC, human placenta, human tonsil tissue, human spleen tissue. |
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| Application Notes | WB:1:1,000-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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