All-trans-retinyl-palmitate hydrolase antibody LCA 2 antibody LCA2 antibody Leber congenital amaurosis antibody mRPE 65 antibody mRPE65 antibody p63 antibody rd 12 antibody rd12 antibody Retinal pigment epithelium specific 61 kDa protein antibody Retinal pigment epithelium specific 65 kDa protein antibody Retinal pigment epithelium specific protein antibody Retinal pigment epithelium specific protein 65kDa antibody Retinal pigment epithelium-specific 65 kDa protein antibody Retinitis pigmentosa 20 antibody Retinoid isomerohydrolase antibody Retinol isomerase antibody RP 20 antibody RP20 antibody RPE 65 antibody RPE65 antibody RPE65_HUMAN antibody sRPE 65 antibody sRPE65 antibody
Product description
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65kDa protein belonging to the beta-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBIP
WB:1:1,000-1:2,000 IP:1:10-1:50
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
All-trans-retinyl-palmitate hydrolase antibody LCA 2 antibody LCA2 antibody Leber congenital amaurosis antibody mRPE 65 antibody mRPE65 antibody p63 antibody rd 12 antibody rd12 antibody Retinal pigment epithelium specific 61 kDa protein antibody Retinal pigment epithelium specific 65 kDa protein antibody Retinal pigment epithelium specific protein antibody Retinal pigment epithelium specific protein 65kDa antibody Retinal pigment epithelium-specific 65 kDa protein antibody Retinitis pigmentosa 20 antibody Retinoid isomerohydrolase antibody Retinol isomerase antibody RP 20 antibody RP20 antibody RPE 65 antibody RPE65 antibody RPE65_HUMAN antibody sRPE 65 antibody sRPE65 antibody
