| 存储条件 |
|---|
| Product Name | Growth Hormone [JM108-09] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Pituitary growth hormone (GH), also designated somatotropin, plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is secreted in a pulsatile pattern which is tightly controlled by the interplay of GH-releasing hormone (GHRH) and somatostatin (SRIF). GHRH and SRIF are the primary hypothalamic factors that determine GH secretion from the somatotroph and regulate GH synthesis and secretory reserve. GH output is also highly sensitive to feedback control by GH itself, as well as by insulin-like growth factor I. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB,IP,IHC |
| WB:1:1,000-1:5,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | gH antibody GH-N antibody GH1 antibody GHB5 antibody GHN antibody Growth hormone 1 antibody Growth hormone antibody Growth hormone B5 antibody Growth hormone normal antibody Growth hormone pituitary antibody HG1 antibody hGH-N antibody IGHD1B antibody Pituitary growth hormone antibody RNGHGP antibody SOMA_HUMAN antibody Somatotropin antibody |
|---|---|
| Molecular Weight(MW) | 25 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | P01241 |
|---|
Application
Fig1: Western blot analysis of Growth Hormone on human placenta cells lysates using anti- Growth Hormone antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.| Positive Control | Human placenta, human liver cancer tissue, human tonsil tissue, human breast tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
