| 存储条件 |
|---|
| Product Name | Claudin 5 [JM11-22] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Androgen withdrawal and apoptosis induced protein RVP1 like antibody AWAL antibody BEC 1 antibody BEC1 antibody Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody Claudin-5 antibody Claudin5 antibody CLD5_HUMAN antibody CLDN 5 antibody Cldn5 antibody CPETR L1 antibody CPETRL 1 antibody CPETRL1 antibody TMDVCF antibody TMVCF antibody Transmembrane protein deleted in VCFS antibody Transmembrane protein deleted in velocardiofacial syndrome antibody |
| Product description | The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-5 is expressed in the endothelial junctions of the rat liver and in junctions of acinar cells of the pancreas. Human Claudin-5 is abundantly expressed in adult lung, heart and skeletal muscle and is deleted in patients with velocardiofacial syndrone, which is characterized by cleft palate, facial dysmorphology and conotruncal heart defects. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:2,000-1:5,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Androgen withdrawal and apoptosis induced protein RVP1 like antibody AWAL antibody BEC 1 antibody BEC1 antibody Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody Claudin-5 antibody Claudin5 antibody CLD5_HUMAN antibody CLDN 5 antibody Cldn5 antibody CPETR L1 antibody CPETRL 1 antibody CPETRL1 antibody TMDVCF antibody TMVCF antibody Transmembrane protein deleted in VCFS antibody Transmembrane protein deleted in velocardiofacial syndrome antibody |
|---|---|
| Molecular Weight(MW) | 24 kDa |
| Cellular Localization | Cell junction. Cell membrane. |
| SwissProt ID | O00501 |
|---|
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Claudin 5 antibody. Counter stained with hematoxylin.| Positive Control | Human lung cells lysates, human tonsil tissue, human kidney tissue, human lung tissue, human uterus tissue. |
|---|---|
| Application Notes | WB:1:2,000-1:5,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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