| 存储条件 |
|---|
| Product Name | CD41 [JM11-19] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | antigen CD41 antibody BDPLT16 antibody BDPLT2 antibody CD41 antibody CD41B antibody form 2 antibody GP2B antibody GPalpha IIb antibody GPIIb antibody GT antibody GTA antibody HPA3 antibody Integrin alpha 2b antibody Integrin alpha IIb antibody Integrin alpha-IIb light chain antibody Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody ITA2B_HUMAN antibody Itga2b antibody ITGAB antibody platelet fibrinogen receptor, alpha subunit antibody platelet glycoprotein IIb of IIb/IIIa complex antibody Platelet membrane glycoprotein IIb antibody platelet specific antigen BAK antibody PPP1R93 antibody |
| Product description | Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | antigen CD41 antibody BDPLT16 antibody BDPLT2 antibody CD41 antibody CD41B antibody form 2 antibody GP2B antibody GPalpha IIb antibody GPIIb antibody GT antibody GTA antibody HPA3 antibody Integrin alpha 2b antibody Integrin alpha IIb antibody Integrin alpha-IIb light chain antibody Integrin alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex antigen CD41) antibody ITA2B_HUMAN antibody Itga2b antibody ITGAB antibody platelet fibrinogen receptor alpha subunit antibody platelet glycoprotein IIb of IIb/IIIa complex antibody Platelet membrane glycoprotein IIb antibody platelet specific antigen BAK antibody PPP1R93 antibody |
|---|---|
| Molecular Weight(MW) | 113 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | P08514 |
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Application
Fig1: Western blot analysis of CD41 on human placenta cells lysates using anti-CD41 antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD41 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD41 antibody. Counter stained with hematoxylin.| Positive Control | Human tonsil tissue, human spleen tissue, human placenta cells lysates. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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