COAA1_HUMAN antibody Col10a 1 antibody COL10A1 antibody Collagen alpha 1(X) chain antibody Collagen alpha-1(X) chain antibody Collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia) antibody Collagen type X alpha 1 antibody Collagen X alpha 1 polypeptide antibody CollagenX antibody fa66d11 antibody fb10c08 antibody OTTHUMP00000040411 antibody Procollagen type X alpha 1 antibody Schmid metaphyseal chondrodysplasia antibody wu:fa66d11 antibody wu:fb10c08 antibody
Product description
Collagen Type X is associated with hypertrophic chondrocytes of avian and mammalian growth plate tissues during the endochondral growth of long bones. It is a component of normal articular cartilage in adult human, growing pig and newborn rat, and it is also present during any disruption of normal metabolic status of articular cartilage that occur with osteoarthritis. Collagen Type X is composed of three identical a 1(X) chains, each containing a triple-helical region flanked by a short N-terminal sequence and a larger non-collagenous C-terminal (NC1) domain. Mutations in COL10A1, the gene encoding for Collagen Type X, are associated with metaphyseal dysplasia type Schmid (SMCD) and other related forms of metaphyseal dysplasia. SMCD is characterized by short-limbed dwarfism, an outward "flaring" of the lower rib cage, bowed legs, leg pain and a hip deformity that causes the thigh bone to angle toward the center of the body.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WB
WB:1:1,000-1:2,000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
COAA1_HUMAN antibody Col10a 1 antibody COL10A1 antibody Collagen alpha 1(X) chain antibody Collagen alpha-1(X) chain antibody Collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia) antibody Collagen type X alpha 1 antibody Collagen X alpha 1 polypeptide antibody CollagenX antibody fa66d11 antibody fb10c08 antibody OTTHUMP00000040411 antibody Procollagen type X alpha 1 antibody Schmid metaphyseal chondrodysplasia antibody wu:fa66d11 antibody wu:fb10c08 antibody
