| 存储条件 |
|---|
Product Profile
| Product Name | Frizzled-5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C2orf31 antibody DKFZP434E2135 antibody Frizzled 5 seven transmembrane spanning receptor antibody Frizzled class receptor 5 antibody Frizzled family receptor 5 antibody Frizzled homolog 5 antibody Frizzled-5 antibody Frizzled5 antibody Fz 5 antibody Fz-5 antibody Fz5 antibody FZD 5 antibody fzd5 antibody FZD5_HUMAN antibody FzE 5 antibody FzE5 antibody HFZ 5 antibody hFz5 antibody MGC129692 antibody Seven transmembrane receptor frizzled 5 antibody Uncharacterized protein C2orf31 antibody Wnt receptor antibody |
| Product description | Frizzled-5 belongs to the G-protein coupled receptor Fz/Smo family, contains 585 amino acids. It is localized at the plasma membrane and also found at the Golgi. Fzds have a large extracellular N-terminal region containing a cysteine-rich domain (CRD), which is involved in binding to Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. |
| Immunogen | peptide |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:1,000 ICC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
Target Information
| Alternative Names | C2orf31 antibody DKFZP434E2135 antibody Frizzled 5 seven transmembrane spanning receptor antibody Frizzled class receptor 5 antibody Frizzled family receptor 5 antibody Frizzled homolog 5 antibody Frizzled-5 antibody Frizzled5 antibody Fz 5 antibody Fz-5 antibody Fz5 antibody FZD 5 antibody fzd5 antibody FZD5_HUMAN antibody FzE 5 antibody FzE5 antibody HFZ 5 antibody hFz5 antibody MGC129692 antibody Seven transmembrane receptor frizzled 5 antibody Uncharacterized protein C2orf31 antibody Wnt receptor antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| Cellular Localization | Cell membrane |
Database Links
| SwissProt ID | Q13467 |
|---|
Application
Application
Fig1: Western blot analysis on human ES cell using anti-Frizzled-5 polyclonal antibody.
| Positive Control | Human ES cell |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:100-1:200 |
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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