| 存储条件 |
|---|
Product Profile
| Product Name | Transmembrane protein 2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIAA1412 antibody TMEM 2 antibody tmem2 antibody TMEM2_HUMAN antibody Transmembrane protein 2 antibody |
| Product description | Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. |
| Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to transmembrane protein 2. |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:2,000 IHC | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
Target Information
| Alternative Names | KIAA1412 antibody TMEM 2 antibody tmem2 antibody TMEM2_HUMAN antibody Transmembrane protein 2 antibody |
|---|---|
| Molecular Weight(MW) | 150 kDa |
| Cellular Localization | Cell membrane. Membrane. |
Database Links
| SwissProt ID | Q9UHN6Q5FWI3 |
|---|
Application
Application
Fig1: Western blot analysis of TMEM2 on mouse heart tissue lysate using anti-TMEM2 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.
| Positive Control | Mouse heart tissue, rat kidney tissue, human liver tissue, mouse liver tissue, mouse kidney tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 IHC |
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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