| 存储条件 |
|---|
Product Profile
| Product Name | Complement C3(β chain) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Acylation-stimulating protein cleavage product antibody AHUS5 antibody ARMD9 antibody ASP antibody C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody C3 antibody CO3_HUMAN antibody Complement C3 antibody Complement C3 beta chain antibody Complement C3c alpha' chain fragment 2 antibody Complement component 3 antibody Complement component C3 antibody Complement factor 3 antibody CPAMD1 antibody Plp antibody |
| Product description | Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. It’s processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. |
| Immunogen | peptide |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1,000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
Target Information
| Alternative Names | Acylation-stimulating protein cleavage product antibody AHUS5 antibody ARMD9 antibody ASP antibody C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody C3 antibody CO3_HUMAN antibody Complement C3 antibody Complement C3 beta chain antibody Complement C3c alpha' chain fragment 2 antibody Complement component 3 antibody Complement component C3 antibody Complement factor 3 antibody CPAMD1 antibody Plp antibody |
|---|---|
| Molecular Weight(MW) | 70kDa |
| Cellular Localization | Secretory protein |
Database Links
| SwissProt ID | P01024 |
|---|
Application
Application
Fig: Western blot analysis on human serum using anti-complement C3 polyclonal antibody. Note: 50kD band is caused by nonspecific reaction (goat anti-rabbit to human heavy chain).
| Positive Control | human plasma |
|---|---|
| Application Notes | WB:1:1,000 |
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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