| 存储条件 |
|---|
| Product Name | DCAMKL1 [JA11-03] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Calcium/calmodulin-dependent protein kinase type I-like CPG16 antibody CL1 antibody CLICK1 antibody Cpg16 antibody DCDC3A antibody Dcl antibody Dclk antibody Dclk1 antibody DCLK1_HUMAN antibody Doublecortin domain-containing protein 3A antibody Doublecortin-like and CAM kinase-like 1 antibody Doublecortin-like kinase 1 antibody KIAA0369 antibody Serine/threonine-protein kinase DCAMKL1 antibody Serine/threonine-protein kinase DCLK1 antibody |
| Product description | Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, manifesting as severe mental retardation. Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 displays sequence homology to β-subunits of heterotrimeric G proteins, and doublecortin contains a consensus Abl phosphorylation site. In addition, the DCAMKL1 (doublecortinlike and CAM kinase-like 1) protein shows homology to doublecortin. All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration. The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, but its kinase activity does not appear to affect its microtubule polymerization activity. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Calcium/calmodulin-dependent protein kinase type I-like CPG16 antibody CL1 antibody CLICK1 antibody Cpg16 antibody DCDC3A antibody Dcl antibody Dclk antibody Dclk1 antibody DCLK1_HUMAN antibody Doublecortin domain-containing protein 3A antibody Doublecortin-like and CAM kinase-like 1 antibody Doublecortin-like kinase 1 antibody KIAA0369 antibody Serine/threonine-protein kinase DCAMKL1 antibody Serine/threonine-protein kinase DCLK1 antibody |
|---|---|
| Molecular Weight(MW) | 82 kDa |
| Cellular Localization | Plasma membrane. |
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-DCAMKL1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-DCAMKL1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-DCAMKL1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-DCAMKL1 antibody. Counter stained with hematoxylin.| Positive Control | Human spleen tissue, rat testis tissue, mouse prostate tissue, mouse brain tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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