| 存储条件 |
|---|
| Product Name | CD18 [JM71-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 95 subunit beta antibody Beta 2 (antigen CD18 (p95) antibody CD 18 antibody CD18 antibody Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody Complement component 3 receptor 3 and 4 subunit antibody Complement receptor C3 beta subunit antibody Complement receptor C3 subunit beta antibody Integrin beta 2 antibody Integrin beta chain beta 2 antibody Integrin beta-2 (ITGB2) antibody Integrin beta-2 antibody Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody ITB2_HUMAN antibody ITGB2 antibody LAD antibody LCAMB antibody Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody Leukocyte cell adhesion molecule CD18 antibody LFA 1 antibody LFA1 antibody Lymphocyte function associated antigen 1 (LFA1) antibody Lymphocyte function associated antigen 1 antibody MAC 1 antibody MAC1 antibody Macrophage antigen 1 (mac1) beta antibody MF17 antibody MFI7 antibody OTTHUMP00000115278 antibody OTTHUMP00000115279 antibody OTTHUMP00000115280 antibody OTTHUMP00000115281 antibody OTTHUMP00000115282 antibody |
| Product description | Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIP |
| WB:1:500-1:1,000 IP:1:10-1:50 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | 95 subunit beta antibody Beta 2 (antigen CD18 (p95) antibody CD 18 antibody CD18 antibody Cell surface adhesion glycoprotein LFA 1/CR3/P150 959 beta subunit precursor) antibody Cell surface adhesion glycoproteins LFA 1/CR3/p150 95 subunit beta antibody Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody Complement component 3 receptor 3 and 4 subunit antibody Complement receptor C3 beta subunit antibody Complement receptor C3 subunit beta antibody Integrin beta 2 antibody Integrin beta chain beta 2 antibody Integrin beta-2 (ITGB2) antibody Integrin beta-2 antibody Integrin beta 2 (complement component 3 receptor 3 and 4 subunit) antibody ITB2_HUMAN antibody ITGB2 antibody LAD antibody LCAMB antibody Leukocyte associated antigens CD18/11A CD18/11B CD18/11C antibody Leukocyte cell adhesion molecule CD18 antibody LFA 1 antibody LFA1 antibody Lymphocyte function associated antigen 1 (LFA1) antibody Lymphocyte function associated antigen 1 antibody MAC 1 antibody MAC1 antibody Macrophage antigen 1 (mac1) beta antibody MF17 antibody MFI7 antibody OTTHUMP00000115278 antibody OTTHUMP00000115279 antibody OTTHUMP00000115280 antibody OTTHUMP00000115281 antibody OTTHUMP00000115282 antibody |
|---|---|
| Molecular Weight(MW) | 95 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | P05107 |
|---|
Application
Fig1: Western blot analysis of CD18 on Jurkat cells lysates using anti-CD18 antibody at 1/500 dilution.| Positive Control | Jurkat. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IP:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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