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| Product Name | AQP1 [JM10-98] |
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| Antibody Type | Primary Antibodies |
| Antigen Alias | AQP 1 antibody AQP CHIP antibody AQP-1 antibody AQP1 antibody AQP1_HUMAN antibody aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group) antibody aquaporin 1 (Colton blood group) antibody Aquaporin CHIP antibody Aquaporin-1 antibody Aquaporin-CHIP antibody Aquaporin1 antibody Channel forming integral protein 28kDa antibody Channel like integral membrane protein 28 kDa antibody CHIP 28 antibody CHIP28 antibody CO antibody Colton blood group antibody Growth factor induced delayed early response protein antibody MGC26324 antibody Urine water channel antibody Water channel protein CHIP 29 antibody Water channel protein CHIP29 antibody Water channel protein for red blood cells and kidney proximal tubule antibody |
| Product description | Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of Aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most Aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. AQP1 is an integral membrane protein expressed in erythrocytes and renal tubule cells. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
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| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IFIHC |
| WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | AQP 1 antibody AQP CHIP antibody AQP-1 antibody AQP1 antibody AQP1_HUMAN antibody aquaporin 1 (channel-forming integral protein 28kDa CO blood group) antibody aquaporin 1 (Colton blood group) antibody Aquaporin CHIP antibody Aquaporin-1 antibody Aquaporin-CHIP antibody Aquaporin1 antibody Channel forming integral protein 28kDa antibody Channel like integral membrane protein 28 kDa antibody CHIP 28 antibody CHIP28 antibody CO antibody Colton blood group antibody Growth factor induced delayed early response protein antibody MGC26324 antibody Urine water channel antibody Water channel protein CHIP 29 antibody Water channel protein CHIP29 antibody Water channel protein for red blood cells and kidney proximal tubule antibody |
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| Molecular Weight(MW) | 28/35 kDa |
| Cellular Localization | Membrane. |
Application
Fig1: Western blot analysis of AQP1 on different cells lysates using anti-AQP1 antibody at 1/500 dilution. Positive control: Line 1: Hela Line 2:Jurkat Line 3: Human kidney
Application
Fig2: ICC staining AQP1 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining AQP1 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining AQP1 in SW480 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-AQP1 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-AQP1 antibody. Counter stained with hematoxylin.
Application
Fig7: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-AQP1 antibody. Counter stained with hematoxylin.
Application
Fig8: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-AQP1 antibody. Counter stained with hematoxylin.
Application
Fig9: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-AQP1 antibody. Counter stained with hematoxylin.
Application
Fig10: Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-AQP1 antibody. Counter stained with hematoxylin.| Positive Control | Jurkat, MCF-7, SW480, Hela, human spleen tissue, human kidney tissue, human bresst tissue, human pancreas tissue, mouse skeletal muscle tissue, mouse colon tissue. |
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| Application Notes | WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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