| 存储条件 |
|---|
| Product Name | Jagged1 [JF96-06] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AGS antibody AHD antibody AWS antibody CD 339 antibody CD339 antibody CD339 antigen antibody Headturner antibody hJ1 antibody Htu antibody Jag 1 antibody Jag1 antibody JAG1_HUMAN antibody Jagged 1 antibody Jagged1 (Alagille syndrome) antibody Jagged1 antibody JAGL1 antibody MGC104644 antibody OTTHUMP00000030278 antibody Protein jagged-1 antibody Ser 1 antibody Ser1 antibody Serrate 1 antibody Slalom antibody |
| Product description | The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged is a membrane protein and can activate Notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis. Jagged is expressed in adult and fetal tissues, and expression is upregulated in cervical squamous cell carcinoma. Familial Tetralogy of Fallot, the most common form of complex congenital heart disease, is caused by a mutation in the Jagged1 gene. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | AGS antibody AHD antibody AWS antibody CD 339 antibody CD339 antibody CD339 antigen antibody Headturner antibody hJ1 antibody Htu antibody Jag 1 antibody Jag1 antibody JAG1_HUMAN antibody Jagged 1 antibody Jagged1 (Alagille syndrome) antibody Jagged1 antibody JAGL1 antibody MGC104644 antibody OTTHUMP00000030278 antibody Protein jagged-1 antibody Ser 1 antibody Ser1 antibody Serrate 1 antibody Slalom antibody |
|---|---|
| Molecular Weight(MW) | 134 kDa |
| Cellular Localization | Membrane. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Jagged1 antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Jagged1 antibody. Counter stained with hematoxylin.| Positive Control | Human kidney tissue, mouse kidney tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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