ACKR3 antibody atypical chemokine receptor 3 antibody C X C chemokine receptor type 7 antibody C-X-C chemokine receptor type 7 antibody Chemokine (C-X-C motif) receptor 7 antibody Chemokine C X C motif receptor 7 antibody Chemokine orphan receptor 1 antibody CMKOR1 antibody CXC R7 antibody CXC-R7 antibody CXCR 7 antibody CXCR-7 antibody CXCR7 antibody CXCR7_HUMAN antibody G protein coupled receptor 159 antibody G protein coupled receptor antibody G protein coupled receptor RDC1 homolog antibody G-protein coupled receptor 159 antibody G-protein coupled receptor RDC1 homolog antibody GPR159 antibody GPRN1 antibody RDC 1 antibody RDC-1 antibody RDC1 antibody
Product description
Members of the C-X-C or α chemokine family are characterized by a pair of cysteine residues separated by a single amino acid and primarily function as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins and include proteins such as IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). C-X-C chemokine receptor type 7 (CXCR-7), also known as RDC-1, is a 362 amino acid receptor for SDF-1. Initially identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor. CXCR-7, with CSCR-4, also acts as a coreceptor for human immunodeficiency viruses (HIV). Highly expressed in monocytes, B-cells and basophils, and highly active in various biological processes, including cell growth, cell adhesion and tumor growth, CXCR-7 may play a role in tumorigenesis.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBFC
WB:1:1,000-1:5,000 FC:1:10-1:100
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
ACKR3 antibody atypical chemokine receptor 3 antibody C X C chemokine receptor type 7 antibody C-X-C chemokine receptor type 7 antibody Chemokine (C-X-C motif) receptor 7 antibody Chemokine C X C motif receptor 7 antibody Chemokine orphan receptor 1 antibody CMKOR1 antibody CXC R7 antibody CXC-R7 antibody CXCR 7 antibody CXCR-7 antibody CXCR7 antibody CXCR7_HUMAN antibody G protein coupled receptor 159 antibody G protein coupled receptor antibody G protein coupled receptor RDC1 homolog antibody G-protein coupled receptor 159 antibody G-protein coupled receptor RDC1 homolog antibody GPR159 antibody GPRN1 antibody RDC 1 antibody RDC-1 antibody RDC1 antibody
Fig1: Western blot analysis of GPCR RDC1 on PC-3M cells lysates using anti-GPCR RDC1 antibody at 1/1,000 dilution.
Application
Fig2: Flow cytometric analysis of Jurkat cells with GPCR RDC1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Positive Control
PC-3M.
Application Notes
WB:1:1,000-1:5,000 FC:1:10-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
