ER BETA antibody ER-beta antibody Erb antibody ESR B antibody ESR BETA antibody ESR2 antibody ESR2_HUMAN antibody ESRB antibody ESTRB antibody estrogen nuclear receptor beta variant a antibody estrogen nuclear receptor beta variant b antibody estrogen receptor 2 (ER beta) antibody Estrogen receptor 2 antibody estrogen receptor beta 4 antibody Estrogen receptor beta antibody NR3A2 antibody Nuclear receptor subfamily 3 group A member 2 antibody
Product description
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WB
WB:1:1,000-1:2,000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
ER BETA antibody ER-beta antibody Erb antibody ESR B antibody ESR BETA antibody ESR2 antibody ESR2_HUMAN antibody ESRB antibody ESTRB antibody estrogen nuclear receptor beta variant a antibody estrogen nuclear receptor beta variant b antibody estrogen receptor 2 (ER beta) antibody Estrogen receptor 2 antibody estrogen receptor beta 4 antibody Estrogen receptor beta antibody NR3A2 antibody Nuclear receptor subfamily 3 group A member 2 antibody
