| 存储条件 |
|---|
| Product Name | Carbonic anhydrase 9 [JJ088-9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CA-IX antibody CA9 antibody CAH9_HUMAN antibody CAIX antibody Carbonate dehydratase IX antibody Carbonic anhydrase 9 antibody Carbonic anhydrase IX antibody Carbonic dehydratase antibody G250 antibody Membrane antigen MN antibody MN antibody P54/58N antibody pMW1 antibody RCC associated protein G250 antibody RCC-associated antigen G250 antibody Renal cell carcinoma-associated antigen G250 antibody |
| Product description | Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes including respiration, calcification, acid-base balance and bone resorption, as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA2 gene, which maps to chromosome 8q21, encodes CA II, a cytoplasmic protein that has the highest turnover rate and widest tissue distribution of any known human CA isozyme. The human CA4 gene, which maps to chromosome 17q23, encodes CA IV, a membrane-anchored isozyme that is expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. The human CA9, CA12 and CA14 genes, which map to chromosomes 9p13, 15q22 and 1q21, respectively, encode transmembrane proteins that have unique patterns of tissue-specific expression. CA IX is specifically expressed in clear-cell renal carcinomas, whereas CA XII is highly expressed in normal tissues, such as kidney, colon and pancreas. Human CA XIV is also expressed in normal tissues, such as brain, but differs from CA XII in its expression pattern. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:2,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CA-IX antibody CA9 antibody CAH9_HUMAN antibody CAIX antibody Carbonate dehydratase IX antibody Carbonic anhydrase 9 antibody Carbonic anhydrase IX antibody Carbonic dehydratase antibody G250 antibody Membrane antigen MN antibody MN antibody P54/58N antibody pMW1 antibody RCC associated protein G250 antibody RCC-associated antigen G250 antibody Renal cell carcinoma-associated antigen G250 antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| Cellular Localization | Nucleus, Cell membrane, Cell projection. |
| SwissProt ID | Q16790 |
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Application
Fig1: Western blot analysis of Carbonic anhydrase 9 on human lung lysates using anti- Carbonic anhydrase 9 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- Carbonic anhydrase 9 antibody. Counter stained with hematoxylin.| Positive Control | Human lung tissue, human liver cancer tissue. |
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| Application Notes | WB:1:1,000-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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