D-OR-1 antibody Delta type opioid receptor antibody Delta type opioid receptor DOR 1 antibody Delta type opioid receptor DOR1 antibody Delta-type opioid receptor antibody DOR 1 antibody DOR-1 antibody DOR1 antibody mDOR antibody Nbor antibody Opioid receptor delta 1 antibody OPRD 1 antibody OPRD antibody OPRD_HUMAN antibody Oprd1 antibody
Product description
Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins. The three opioid receptor types are highly homologous and belong to the superfamily of G protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBFC
WB:1:1,000 FC:1:50-1:100
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
D-OR-1 antibody Delta type opioid receptor antibody Delta type opioid receptor DOR 1 antibody Delta type opioid receptor DOR1 antibody Delta-type opioid receptor antibody DOR 1 antibody DOR-1 antibody DOR1 antibody mDOR antibody Nbor antibody Opioid receptor delta 1 antibody OPRD 1 antibody OPRD antibody OPRD_HUMAN antibody Oprd1 antibody
Fig1: Western blot analysis of OPRD1 on different lysates using anti-OPRD1 antibody at 1/1,000 dilution. Positive control: Lane 1: HUVEC Lane 2: Rat brain
Application
Fig2: Flow cytometric analysis of SH-SY-5Y cells with OPRD1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Positive Control
HUVEC, rat brain tissue.
Application Notes
WB:1:1,000 FC:1:50-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
