| 存储条件 |
|---|
| Product Name | Phospho-Synapsin Ⅰ (S9) [SN63-04] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Brain protein 4.1 antibody SYN 1 antibody SYN 1a antibody SYN 1b antibody SYN I antibody SYN1 antibody SYN1_HUMAN antibody SYN1a antibody SYN1b antibody Synapsin 1 antibody Synapsin I antibody Synapsin-1 antibody Synapsin1 antibody SynapsinI antibody SYNI antibody |
| Product description | Synapsins are synaptic vesicle-associated phosphoproteins that regulate synaptic vesicle exocytosis and may be involved in synaptogenesis. Evidence suggests that Synapsin I, Synapsin II and Synapsin IIIa are ATP-binding proteins that are regulated by Ca2+ and calmodulin binding. Ca2+ has been shown to stimulate ATP binding to Synapsin I, to have no effect on Synapsin II and to inhibit Synapsin III. Synapsin I and Synapsin II both undergo alternative splicing to produce two forms of each protein, Synapsin la and lb and Synapsin IIa and IIb, respectively. Synapsin III gives rise to at least three isoforms: Synapsin IIIa, IIIb and IIIc. Synapsin III plays unique roles both in early axon outgrowth and in the regulation of synaptic vesicle trafficking. In cultured mouse hippocampal neurons, Synapsin III is expressed early during development, with levels peaking seven days after plating and declining thereafter. Synapsin III is highly concentrated in growth cones. |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser9 of human SynapsinⅠ |
| Modification | p-S9 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Brain protein 4.1 antibody SYN 1 antibody SYN 1a antibody SYN 1b antibody SYN I antibody SYN1 antibody SYN1_HUMAN antibody SYN1a antibody SYN1b antibody Synapsin 1 antibody Synapsin I antibody Synapsin-1 antibody Synapsin1 antibody SynapsinI antibody SYNI antibody |
|---|---|
| Molecular Weight(MW) | 77 kDa |
| Cellular Localization | Cell junction, Golgi apparatus. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti- phospho-Synapsin Ⅰ (S9) antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti- phospho-Synapsin Ⅰ (S9) antibody. Counter stained with hematoxylin.| Positive Control | Rat brain tissue, mouse brain tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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