KCD2 antibody KCND 2 antibody KCND2 antibody KCND2_HUMAN antibody KIAA1044 antibody MGC119702 antibody MGC119703 antibody Potassium voltage gated channel Shal related subfamily member 2 antibody Potassium voltage-gated channel subfamily D member 2 antibody RK 5 antibody RK5 antibody Voltage gated potassium channel Kv4.2 antibody Voltage gated potassium channel subunit Kv4.2 antibody Voltage sensitive potassium channel antibody Voltage-gated potassium channel subunit Kv4.2 antibody
Product description
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming α-subunits (KVα), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
Immunogen
Recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
WBFC
WB:1:500-1:2,000 FC:1:50-1:100
Species Reactivity
Human
Concentration
2mg/ml
Target Information
Alternative Names
KCD2 antibody KCND 2 antibody KCND2 antibody KCND2_HUMAN antibody KIAA1044 antibody MGC119702 antibody MGC119703 antibody Potassium voltage gated channel Shal related subfamily member 2 antibody Potassium voltage-gated channel subfamily D member 2 antibody RK 5 antibody RK5 antibody Voltage gated potassium channel Kv4.2 antibody Voltage gated potassium channel subunit Kv4.2 antibody Voltage sensitive potassium channel antibody Voltage-gated potassium channel subunit Kv4.2 antibody
Fig1: Western blot analysis of Kv4.2 on human Kv4.2 recombinant protein using anti- Kv4.2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of Kv4.2 on HEK293 (1) and Kv4.2-hIgGFc transfected HEK293 (2) cell lysate using anti- Kv4.2 antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with Kv4.2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control
Human Kv4.2 recombinant protein, KCND2-hIgGFc transfected HEK293 cell lysate, Hela.
Application Notes
WB:1:500-1:2,000 FC:1:50-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
