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Product Profile
| Product Name | TGF-Beta 1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cartilage-inducing factor antibody CED antibody Differentiation inhibiting factor antibody DPD1 antibody LAP antibody Latency-associated peptide antibody Prepro transforming growth factor beta 1 antibody TGF beta 1 antibody TGF beta antibody TGF beta 1 protein antibody TGF-beta 1 protein antibody TGF-beta-1 antibody TGF-beta-5 antibody TGF-beta1 antibody TGFB antibody Tgfb-1 antibody tgfb1 antibody TGFB1_HUMAN antibody TGFbeta antibody TGFbeta1 antibody Transforming Growth Factor b1 antibody Transforming Growth Factor beta 1 antibody Transforming growth factor beta 1a antibody transforming growth factor beta-1 antibody transforming growth factor, beta 1 antibody Transforming Growth Factor-?1 antibody |
| Product description | Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN. Function: TGF beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. Tissue specificity: TGF beta 1 is highly expressed in bone. A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. |
| Immunogen | peptide |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:200 IHC:1:200 FC:1:100: | |
| Species Reactivity | HumanMouseRatZebra Fish |
| Concentration | 1mg/ml |
Target Information
| Alternative Names | Cartilage-inducing factor antibody CED antibody Differentiation inhibiting factor antibody DPD1 antibody LAP antibody Latency-associated peptide antibody Prepro transforming growth factor beta 1 antibody TGF beta 1 antibody TGF beta antibody TGF beta 1 protein antibody TGF-beta 1 protein antibody TGF-beta-1 antibody TGF-beta-5 antibody TGF-beta1 antibody TGFB antibody Tgfb-1 antibody tgfb1 antibody TGFB1_HUMAN antibody TGFbeta antibody TGFbeta1 antibody Transforming Growth Factor b1 antibody Transforming Growth Factor beta 1 antibody Transforming growth factor beta 1a antibody transforming growth factor beta-1 antibody transforming growth factor beta 1 antibody Transforming Growth Factor-?1 antibody |
|---|---|
| Molecular Weight(MW) | 44 kDa |
| Cellular Localization | Secreted |
Database Links
| SwissProt ID | P01137 |
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Application
Application
Fig1: Western blot analysis of TGF-Beta 1 on different cell lysates using anti- TGF-Beta 1 antibody at 1/1000 dilution. Positive control: Lane 1: Raji Lane 2: MCF-2 Lane 3: A549 Lane 4: Human kidney
Application
Fig2: ICC staining TGF-Beta 1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining TGF-Beta 1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining TGF-Beta 1 in SKBR-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TGF-Beta 1 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-TGF-Beta 1 antibody. Counter stained with hematoxylin.
Application
Fig7: Flow cytometric analysis of HepG2 cells with TGF-Beta 1 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.
| Positive Control | Raji, MCF-7, A549, human kidney tissue, mouse kidney tissue, SKBR-3, Hela, HepG2 |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:200 IHC:1:200 FC:1:100: |
Additional Information
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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