| 存储条件 |
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Product Profile
| Product Name | IL-7R-alpha |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD 127 antibody CD127 antibody CD127 antigen antibody CDw127 antibody IL 7R alpha antibody IL 7R antibody IL-7 receptor subunit alpha antibody IL-7R subunit alpha antibody IL-7R-alpha antibody IL-7RA antibody IL7R antibody IL7RA antibody IL7RA_HUMAN antibody IL7Ralpha antibody ILRA antibody Interleukin 7 receptor alpha chain antibody Interleukin 7 receptor antibody Interleukin 7 receptor isoform H5 6 antibody Interleukin-7 receptor subunit alpha antibody |
| Product description | Interleukin 7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor g chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of insulin receptor substrate-1 (IRS-1) and insulin receptor substrate-2 (IRS-2), originally called 4PS. |
| Immunogen | Recombinant protein |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | HumanZebra Fish |
| Concentration | 1mg/ml |
Target Information
| Alternative Names | CD 127 antibody CD127 antibody CD127 antigen antibody CDw127 antibody IL 7R alpha antibody IL 7R antibody IL-7 receptor subunit alpha antibody IL-7R subunit alpha antibody IL-7R-alpha antibody IL-7RA antibody IL7R antibody IL7RA antibody IL7RA_HUMAN antibody IL7Ralpha antibody ILRA antibody Interleukin 7 receptor alpha chain antibody Interleukin 7 receptor antibody Interleukin 7 receptor isoform H5 6 antibody Interleukin-7 receptor subunit alpha antibody |
|---|---|
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Membrane. Secreted. |
Database Links
| SwissProt ID | P16871E9QDP8 |
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Application
Application
Fig1: Western blot analysis of IL-7R-alpha on zebrafish tissue lysate using anti-IL-7R-alpha antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded zebrafish tissue using anti-IL-7R-alpha antibody. Counter stained with hematoxylin.
Application
Fig3: Flow cytometric analysis of Daudi cells with IL-7R-alpha antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
| Positive Control | Zebrafish, Daudi. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 |
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
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