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Product Profile
| Product Name | VDAC1 [SA93-03] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | N2441 antibody OMP2 antibody POR1 antibody hVDAC1 antibody MGC111064 antibody Mitochondrial Porin antibody Outer mitochondrial membrane protein porin 1 antibody Plasmalemmal porin antibody Porin 31HL antibody Porin 31HM antibody VDAC antibody VDAC-1 antibody Vdac1 antibody VDAC1_HUMAN antibody Voltage dependent anion channel 1 antibody Voltage dependent anion selective channel protein 1 antibody Voltage-dependent anion-selective channel protein 1 antibody YNL055C antibody YNL2441C antibody |
| Product description | Voltage-dependent anion-selective channel (VDAC1) (also referred to as porin, isoform 1) is a small protein, originally discovered in the outer membrane of mitochondria where it constitutes the major pore-forming protein. The porin protein VDAC1 allows to the outer-most membrane of the mitochondrion free permeability to low molecular-weight solutes. VDAC1 has been shown to co-immunoprecipitate with the anti-apoptotic protein Bcl-2 and suggested to be involved in forming the mitochondrial pore which releases cytochrome c during apoptosis. |
| Immunogen | recombinant protein |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:5,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
Target Information
| Alternative Names | N2441 antibody OMP2 antibody POR1 antibody hVDAC1 antibody MGC111064 antibody Mitochondrial Porin antibody Outer mitochondrial membrane protein porin 1 antibody Plasmalemmal porin antibody Porin 31HL antibody Porin 31HM antibody VDAC antibody VDAC-1 antibody Vdac1 antibody VDAC1_HUMAN antibody Voltage dependent anion channel 1 antibody Voltage dependent anion selective channel protein 1 antibody Voltage-dependent anion-selective channel protein 1 antibody YNL055C antibody YNL2441C antibody |
|---|---|
| Molecular Weight(MW) | 31 kDa |
| Cellular Localization | Mitochondrion outer membrane, Cell membrane, Membrane raft |
Database Links
| SwissProt ID | P21796Q60932Q9Z2L0 |
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Application
Application
Fig1: Western blot analysis of VDAC1 on different cell lysates using anti-VDAC1 antibody at 1/1,000 dilution. Positive control: Lane 1: Raji Lane 2: HepG2 Lane 3: SW480
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
| Positive Control | Raji, SW480, HepG2, human liver tissue, mouse liver tissue, mouse kidney tissue, human kidney tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 IHC:1:50-1:200 |
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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